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A Role for Jag2 in Promoting Uveal Melanoma Dissemination and Growth

PURPOSE. Controlling the spread of uveal melanoma is key to improving survival of patients with this common intraocular malignancy. The Notch ligand Jag2 has been shown to be upregulated in primary tumors that metastasize, and we therefore investigated its role in promoting invasion and clonogenic g...

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Publicado en:Invest Ophthalmol Vis Sci
Autores principales: Asnaghi, Laura, Handa, James T., Merbs, Shannath L., Harbour, J. William, Eberhart, Charles G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604713/
https://ncbi.nlm.nih.gov/pubmed/23211831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10209
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