Notch Signaling Promotes Growth and Invasion in Uveal Melanoma

PURPOSE: To determine whether uveal melanoma, the most common primary intraocular malignancy in adults, requires Notch activity for growth and metastasis. EXPERIMENTAL DESIGN: Expression of Notch pathway members was characterized in primary tumor samples and in cell lines, along with the effects of...

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Dettagli Bibliografici
Pubblicato in:Clin Cancer Res
Autori principali: Asnaghi, Laura, Ebrahimi, Katayoon B., Schreck, Karisa C., Bar, Eli E., Coonfield, Michael L., Bell, W. Robert, Handa, James, Merbs, Shannath L., Harbour, J. William, Eberhart, Charles G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648284/
https://ncbi.nlm.nih.gov/pubmed/22228632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1406
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