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Notch3 Activation Promotes Invasive Glioma Formation in a Tissue Site-Specific Manner

While Notch signaling has been widely implicated in neoplastic growth, direct evidence for in vivo initiation of neoplasia by the pathway in murine models has been limited to tumors of lymphoid, breast, and choroid plexus cells. To examine tumorigenic potential in the eye and brain, we injected retr...

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Bibliografiske detaljer
Main Authors: Pierfelice, Tarran J., Schreck, Karisa C., Dang, Louis, Asnaghi, Laura, Gaiano, Nicholas, Eberhart, Charles G.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076023/
https://ncbi.nlm.nih.gov/pubmed/21245095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0690
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