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Validation of the In Vivo Assessment of Pyruvate Dehydrogenase Activity Using Hyperpolarized (13)C-Magnetic Resonance Spectroscopy

AIM: Many diseases of the heart are characterised by changes in substrate utilisation, which is in part regulated by the activity of the enzyme pyruvate dehydrogenase (PDH). Consequently, there is much interest in the in vivo evaluation of PDH activity in a range of physiological and pathological st...

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Publicat a:NMR Biomed
Autors principals: Atherton, Helen J., Schroeder, Marie A., Dodd, Michael S., Heather, Lisa C., Carter, Emma E., Cochlin, Lowri E., Nagel, Simon, Sibson, Nicola R., Radda, George K., Clarke, Kieran, Tyler, Damian J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604661/
https://ncbi.nlm.nih.gov/pubmed/20799252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.1573
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