NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer

BACKGROUND: Brain metastases are an increasing problem in women with invasive breast cancer. Strategies designed to treat brain metastases of breast cancer, particularly chemotherapeutics such as irinotecan, demonstrate limited efficacy. Conventional irinotecan distributes poorly to brain metastases...

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Bibliografiska uppgifter
I publikationen:BMC Cancer
Huvudupphovsmän: Adkins, Chris E., Nounou, Mohamed I., Hye, Tanvirul, Mohammad, Afroz S., Terrell-Hall, Tori, Mohan, Neel K., Eldon, Michael A., Hoch, Ute, Lockman, Paul R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
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Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604629/
https://ncbi.nlm.nih.gov/pubmed/26463521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1672-4
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