NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer

BACKGROUND: Brain metastases are an increasing problem in women with invasive breast cancer. Strategies designed to treat brain metastases of breast cancer, particularly chemotherapeutics such as irinotecan, demonstrate limited efficacy. Conventional irinotecan distributes poorly to brain metastases...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Adkins, Chris E., Nounou, Mohamed I., Hye, Tanvirul, Mohammad, Afroz S., Terrell-Hall, Tori, Mohan, Neel K., Eldon, Michael A., Hoch, Ute, Lockman, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604629/
https://ncbi.nlm.nih.gov/pubmed/26463521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1672-4
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