NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer

BACKGROUND: Brain metastases are an increasing problem in women with invasive breast cancer. Strategies designed to treat brain metastases of breast cancer, particularly chemotherapeutics such as irinotecan, demonstrate limited efficacy. Conventional irinotecan distributes poorly to brain metastases...

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Foilsithe in:BMC Cancer
Main Authors: Adkins, Chris E., Nounou, Mohamed I., Hye, Tanvirul, Mohammad, Afroz S., Terrell-Hall, Tori, Mohan, Neel K., Eldon, Michael A., Hoch, Ute, Lockman, Paul R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604629/
https://ncbi.nlm.nih.gov/pubmed/26463521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1672-4
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