NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer

BACKGROUND: Brain metastases are an increasing problem in women with invasive breast cancer. Strategies designed to treat brain metastases of breast cancer, particularly chemotherapeutics such as irinotecan, demonstrate limited efficacy. Conventional irinotecan distributes poorly to brain metastases...

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Опубликовано в: :BMC Cancer
Главные авторы: Adkins, Chris E., Nounou, Mohamed I., Hye, Tanvirul, Mohammad, Afroz S., Terrell-Hall, Tori, Mohan, Neel K., Eldon, Michael A., Hoch, Ute, Lockman, Paul R.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604629/
https://ncbi.nlm.nih.gov/pubmed/26463521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1672-4
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