Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication

Accurate completion of replication relies on the ability of cells to activate error-free recombination-mediated DNA damage bypass at sites of perturbed replication. However, as anti-recombinase activities are also recruited to replication forks, how recombination-mediated damage bypass is enabled at...

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Publicat a:Genes Dev
Autors principals: Urulangodi, Madhusoodanan, Sebesta, Marek, Menolfi, Demis, Szakal, Barnabas, Sollier, Julie, Sisakova, Alexandra, Krejci, Lumir, Branzei, Dana
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604347/
https://ncbi.nlm.nih.gov/pubmed/26443850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.265629.115
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