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Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice
Amyloidopathy involves the accumulation of insoluble amyloid β (Aβ) species in the brain’s parenchyma and is a key histopathological hallmark of Alzheimer’s disease (AD). Work on transgenic mice that overexpress Aβ suggests that elevated Aβ levels in the brain are associated with aberrant epileptifo...
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| Pubblicato in: | Front Cell Neurosci |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4604241/ https://ncbi.nlm.nih.gov/pubmed/26528126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00372 |
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