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Intrinsic excitability changes induced by acute treatment of hippocampal CA1 pyramidal neurons with exogenous amyloid β peptide

Accumulation of beta‐amyloid (Aβ) peptides in the human brain is a canonical pathological hallmark of Alzheimer's disease (AD). Recent work in Aβ‐overexpressing transgenic mice indicates that increased brain Aβ levels can be associated with aberrant epileptiform activity. In line with this, suc...

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Detalhes bibliográficos
Publicado no:Hippocampus
Main Authors: Tamagnini, Francesco, Scullion, Sarah, Brown, Jon T., Randall, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791149/
https://ncbi.nlm.nih.gov/pubmed/25515596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.22403
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