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Design, synthesis, and antitumor evaluation of histone deacetylase inhibitors with l-phenylglycine scaffold
In our previous research, a novel series of histone deacetylase (HDAC) inhibitors with l-phenylglycine scaffold were designed and synthesized, among which amides D3 and D7 and ureido D18 were far superior to the positive control (suberoylanilide hydroxamic acid [SAHA]) in HDAC inhibition, but were o...
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| Publicado no: | Drug Des Devel Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4603714/ https://ncbi.nlm.nih.gov/pubmed/26504374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S94037 |
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