Direct Correlation Between Ligand-Induced α-Synuclein Oligomers and Amyloid-like Fibril Growth

Aggregation of proteins into amyloid deposits is the hallmark of several neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease. The suggestion that intermediate oligomeric species may be cytotoxic has led to intensified investigations of pre-fibrillar oligomers, which are complicate...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Nors Perdersen, Martin, Foderà, Vito, Horvath, Istvan, van Maarschalkerweerd, Andreas, Nørgaard Toft, Katrine, Weise, Christoph, Almqvist, Fredrik, Wolf-Watz, Magnus, Wittung-Stafshede, Pernilla, Vestergaard, Bente
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603703/
https://ncbi.nlm.nih.gov/pubmed/26020724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10422
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