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Ubiquitin ligase Siah2 regulates RevErbα degradation and the mammalian circadian clock

Regulated degradation of proteins by the proteasome is often critical to their function in dynamic cellular pathways. The molecular clock underlying mammalian circadian rhythms relies on the rhythmic expression and degradation of its core components. However, because the tools available for identify...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: DeBruyne, Jason P., Baggs, Julie E., Sato, Trey K., Hogenesch, John B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603519/
https://ncbi.nlm.nih.gov/pubmed/26392558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501204112
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