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Integrative DNA methylation and gene expression analysis to assess the universality of the CpG island methylator phenotype

BACKGROUND: The CpG island methylator phenotype (CIMP) was first characterized in colorectal cancer but since has been extensively studied in several other tumor types such as breast, bladder, lung, and gastric. CIMP is of clinical importance as it has been reported to be associated with prognosis o...

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Detalhes bibliográficos
Publicado no:Hum Genomics
Main Authors: Moarii, Matahi, Reyal, Fabien, Vert, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603341/
https://ncbi.nlm.nih.gov/pubmed/26463173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-015-0048-9
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