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Changes in correlation between promoter methylation and gene expression in cancer
BACKGROUND: Methylation of high-density CpG regions known as CpG Islands (CGIs) has been widely described as a mechanism associated with gene expression regulation. Aberrant promoter methylation is considered a hallmark of cancer involved in silencing of tumor suppressor genes and activation of onco...
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| Pubblicato in: | BMC Genomics |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4625954/ https://ncbi.nlm.nih.gov/pubmed/26510534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1994-2 |
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