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Integrative DNA methylation and gene expression analysis to assess the universality of the CpG island methylator phenotype

BACKGROUND: The CpG island methylator phenotype (CIMP) was first characterized in colorectal cancer but since has been extensively studied in several other tumor types such as breast, bladder, lung, and gastric. CIMP is of clinical importance as it has been reported to be associated with prognosis o...

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Publicat a:Hum Genomics
Autors principals: Moarii, Matahi, Reyal, Fabien, Vert, Jean-Philippe
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603341/
https://ncbi.nlm.nih.gov/pubmed/26463173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-015-0048-9
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