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The CpG island methylator phenotype (CIMP) in colorectal cancer

It is clear that colorectal cancer (CRC) develops through multiple genetic and epigenetic pathways. These pathways may be determined on the basis of three molecular features: (i) mutations in DNA mismatch repair genes, leading to a DNA microsatellite instability (MSI) phenotype, (ii) mutations in AP...

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Hlavní autoři: Mojarad, Ehsan Nazemalhosseini, Kuppen, Peter JK, Aghdaei, Hamid Asadzadeh, Zali, Mohammad Reza
Médium: Artigo
Jazyk:Inglês
Vydáno: Research Institute for Gastroenterology and Liver Diseases 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017514/
https://ncbi.nlm.nih.gov/pubmed/24834258
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