Inhibition of β-catenin–TCF1 interaction delays differentiation of mouse embryonic stem cells

The ability of mouse embryonic stem cells (mESCs) to self-renew or differentiate into various cell lineages is regulated by signaling pathways and a core pluripotency transcriptional network (PTN) comprising Nanog, Oct4, and Sox2. The Wnt/β-catenin pathway promotes pluripotency by alleviating T cell...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Chatterjee, Sujash S., Saj, Abil, Gocha, Tenzin, Murphy, Matthew, Gonsalves, Foster C., Zhang, Xiaoqian, Hayward, Penelope, Akgöl Oksuz, Betül, Shen, Steven S., Madar, Aviv, Martinez Arias, Alfonso, DasGupta, Ramanuj
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602028/
https://ncbi.nlm.nih.gov/pubmed/26459597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201503017
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