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Inhibition of androgen receptor and β-catenin activity in prostate cancer

Androgen receptor (AR) is the major therapeutic target in aggressive prostate cancer. However, targeting AR alone can result in drug resistance and disease recurrence. Therefore, simultaneous targeting of multiple pathways could in principle be an effective approach to treating prostate cancer. Here...

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Détails bibliographiques
Auteurs principaux: Lee, Eugine, Madar, Aviv, David, Gregory, Garabedian, Michael J., DasGupta, Ramanuj, Logan, Susan K.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785716/
https://ncbi.nlm.nih.gov/pubmed/24019458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218168110
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