Impairment of Macrophage Cholesterol Efflux by Cholesterol Hydroperoxide Trafficking: Implications for Atherogenesis Under Oxidative Stress

OBJECTIVE: Oxidative stress associated with cardiovascular disease can produce various oxidized lipids, including cholesterol oxides such as 7-hydroperoxide (7-OOH), 7-hydroxide (7-OH), and 7-ketone (7=O). Unlike 7=O and 7-OH, 7-OOH is redox-active, giving rise to the others via potentially toxic fr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Arterioscler Thromb Vasc Biol
Hauptverfasser: Korytowski, Witold, Wawak, Katarzyna, Pabisz, Pawel, Schmitt, Jared C., Chadwick, Alexandra C., Sahoo, Daisy, Girotti, Albert W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601804/
https://ncbi.nlm.nih.gov/pubmed/26315403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306210
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge