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Surprising Inability of Singlet Oxygen-Generated 6-Hydroperoxycholesterol to Induce Damaging Free Radical Lipid Peroxidation in Cell Membranes
Singlet oxygen attack on cholesterol (Ch), a prominent monounsaturated lipid of mammalian cell plasma membranes, gives rise to three hydroperoxide (ChOOH) isomers, 5α-OOH, 6α-OOH and 6β-OOH, the latter two in lower yield than 5α-OOH, and 6α-OOH in lowest yield. A third possible positional isomer, 7α...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910147/ https://ncbi.nlm.nih.gov/pubmed/20408976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-1097.2010.00722.x |
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