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CHOLESTEROL AS A NATURAL PROBE FOR FREE RADICAL-MEDIATED LIPID PEROXIDATION IN BIOLOGICAL MEMBRANES AND LIPOPROTEINS

We describe a relatively convenient and reliable procedure for assessing the magnitude of free radical-mediated (chain) lipid peroxidation in biological systems. The approach is based on use of radiolabeled cholesterol ([(14)C]Ch) as a probe and determination of well-resolved oxidation intermediates...

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Detalhes bibliográficos
Publicado no:J Chromatogr B Analyt Technol Biomed Life Sci
Main Authors: Girotti, Albert W., Korytowski, Witold
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829455/
https://ncbi.nlm.nih.gov/pubmed/26778710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2015.12.034
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