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Sterol carrier protein-2 (SCP-2) involvement in cholesterol hydroperoxide cytotoxicity as revealed by SCP-2 inhibitor effects

Sterol carrier protein-2 (SCP-2) plays an important role in cholesterol trafficking and metabolism in mammalian cells. The purpose of this study was to determine whether SCP-2, under oxidative stress conditions, might also traffic hydroperoxides of cholesterol, thereby disseminating their cytotoxic...

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Detalhes bibliográficos
Main Authors: Kriska, Tamas, Pilat, Anna, Schmitt, Jared C., Girotti, Albert W.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952558/
https://ncbi.nlm.nih.gov/pubmed/20656919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M008342
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