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Catalytic Kinetic Resolution of Disubstituted Piperidines by Enantioselective Acylation: Synthetic Utility and Mechanistic Insights
The catalytic kinetic resolution of cyclic amines with achiral N-heterocyclic carbenes (NHC) and chiral hydroxamic acids has emerged as a promising method to obtain enantioenriched amines with high selectivity factors. In this report, we describe the catalytic kinetic resolution of disubstituted pip...
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| Gepubliceerd in: | J Am Chem Soc |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601563/ https://ncbi.nlm.nih.gov/pubmed/26308097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b07201 |
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