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Behavioral abnormalities in prion protein knockout mice and the potential relevance of PrP(C) for the cytoskeleton

The cellular prion protein (PrP(C)) is a highly conserved protein, which is anchored to the outer surface of the plasma membrane. Even though its physiological function has already been investigated in different cell or mouse models where PrP(C) expression is either upregulated or depleted, its exac...

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Pubblicato in:Prion
Autori principali: Schmitz, Matthias, Zafar, Saima, Silva, Christopher J, Zerr, Inga
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601510/
https://ncbi.nlm.nih.gov/pubmed/25517431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336896.2014.983746
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