Shedding light on prion disease

Proteolytic processing regulates key processes in health and disease. The cellular prion protein (PrP(C)) is subject to at least 3 cleavage events, α-cleavage, β-cleavage and shedding. In contrast to α- and β-cleavage where there is an ongoing controversy on the identity of relevant proteases, the m...

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Foilsithe in:Prion
Main Authors: Glatzel, Markus, Linsenmeier, Luise, Dohler, Frank, Krasemann, Susanne, Puig, Berta, Altmeppen, Hermann C
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2015
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601257/
https://ncbi.nlm.nih.gov/pubmed/26186508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1065371
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