Efficient PRNP deletion in bovine genome using gene-editing technologies in bovine cells

Even though prion (encoded by the PRNP gene) diseases like bovine spongiform encephalopathy (BSE) are fatal neurodegenerative diseases in cattle, their study via gene deletion has been limited due to the absence of cell lines or mutant models. In this study, we aim to develop an immortalized fibrobl...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Prion
Asıl Yazarlar: Choi, WooJae, Kim, Eunji, Yum, Soo-Young, Lee, ChoongIl, Lee, JiHyun, Moon, JoonHo, Ramachandra, Sisitha, Malaweera, Buddika Oshadi, Cho, JongKi, Kim, Jin-Soo, Kim, SeokJoong, Jang, Goo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2015
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601218/
https://ncbi.nlm.nih.gov/pubmed/26217959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1071459
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