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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
Although cancer arises from a combination of mutations in oncogenes and tumour suppressor genes, the extent to which tumour suppressor gene loss is required for maintaining established tumours is poorly understood. p53 is an important tumour suppressor that acts to restrict proliferation in response...
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| 出版年: | Nature |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601097/ https://ncbi.nlm.nih.gov/pubmed/17251933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05529 |
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