Llwytho...
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants
The c-Myc oncoprotein promotes proliferation and apoptosis, such that mutations that disable apoptotic programmes often cooperate with MYC during tumorigenesis. Here we report that two common mutant MYC alleles derived from human Burkitt’s lymphoma uncouple proliferation from apoptosis and, as a res...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nature |
|---|---|
| Prif Awduron: | , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2005
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4599579/ https://ncbi.nlm.nih.gov/pubmed/16094360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03845 |
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