Lanean...
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants
The c-Myc oncoprotein promotes proliferation and apoptosis, such that mutations that disable apoptotic programmes often cooperate with MYC during tumorigenesis. Here we report that two common mutant MYC alleles derived from human Burkitt’s lymphoma uncouple proliferation from apoptosis and, as a res...
Gorde:
| Argitaratua izan da: | Nature |
|---|---|
| Egile Nagusiak: | , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2005
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4599579/ https://ncbi.nlm.nih.gov/pubmed/16094360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03845 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|