Tumor Necrosis Factor Overcomes Immune Evasion in p53-Mutant Medulloblastoma

Many immunotherapies act by enhancing the ability of cytotoxic T cells to kill tumor cells. Killing depends on T cell recognition of antigens presented by class I major histocompatibility complex (MHC-I) proteins on tumor cells. Here we show that medulloblastomas lacking the p53 tumor suppressor do...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Neurosci
Main Authors: Garancher, Alexandra, Suzuki, Hiromichi, Haricharan, Svasti, Chau, Lianne Q., Masihi, Meher Beigi, Rusert, Jessica M., Norris, Paula S., Carrette, Florent, Romero, Megan M., Morrissy, Sorana A., Skowron, Patryk, Cavalli, Florence M.G., Farooq, Hamza, Ramaswamy, Vijay, Jones, Steven J.M., Moore, Richard A., Mungall, Andrew J., Ma, Yussanne, Thiessen, Nina, Li, Yisu, Morcavallo, Alaide, Qi, Lin, Kogiso, Mari, Du, Yuchen, Baxter, Patricia, Henderson, Jacob J., Crawford, John R., Levy, Michael L., Olson, James M., Cho, Yoon-Jae, Deshpande, Aniruddha J., Li, Xiao-Nan, Chesler, Louis, Marra, Marco A., Wajant, Harald, Becher, Oren J., Bradley, Linda M., Ware, Carl F., Taylor, Michael D., Wechsler-Reya, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456619/
https://ncbi.nlm.nih.gov/pubmed/32424282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-020-0628-4
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares