MBRS-12. A TRANSPOSON MUTAGENESIS SCREEN IDENTIFIES Rreb1 AS A DRIVER FOR GROUP 3 MEDULLOBLASTOMA

Medulloblastoma (MB) is the most common malignant childhood brain tumor. MB can be divided into four major subgroups – WNT, Sonic hedgehog (SHH), Group 3 (G3), and Group 4 (G4) – that exhibit distinct genetic alterations, gene expression profiles, and clinical outcomes. Patients with G3-MB have the...

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發表在:Neuro Oncol
Main Authors: Masihi, Meher Beigi, Lee, Catherine, Furnari, Grace A, Garancher, Alexandra, Wechsler-Reya, Robert J
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
主題:
Medulloblastoma (Research)
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715603/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.529
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