MBRS-60. THE ACTIONABLE GENOMIC LANDSCAPE OF RELAPSED MEDULLOBLASTOMA IS DEFINED BY MAINTENANCE AND ACQUISITION OF DRIVER EVENTS

Medulloblastoma relapse (rMB) occurs in 30–40% of patients and is almost universally fatal. Understanding the genomic landscape of rMB, and its relationship to disease characteristics at diagnosis, will be essential to underpin the development of improved therapeutic strategies, delivered at both di...

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發表在:Neuro Oncol
Main Authors: Richardson, Stacey, Hill, Rebecca M, Kui, Christopher, Lindsey, Janet C, Grabovska, Yura, Schwalbe, Edward C, Hicks, Debbie, Williamson, Daniel, Crosier, Stephen, Joshi, Abjhit, Wharton, Stephen B, Hansford, Jordan, Pizer, Barry, Vinci, Maria, Mastronuzzi, Angela, Carai, Andrea, Michalski, Anthony, Jacques, Thomas S, Bailey, Simon, Clifford, Steven C
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
主題:
Medulloblastoma (Research)
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715322/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.564
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