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Thioxo-dihydroquinazolin-one Compounds as Novel Inhibitors of Myeloperoxidase
[Image: see text] Myeloperoxidase (MPO) is a key antimicrobial enzyme, playing a normal role in host defense, but also contributing to inflammatory conditions including neuroinflammatory diseases such as Parkinson’s and Alzheimer’s. We synthesized and characterized more than 50 quinazolin-4(1H)-one...
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| Publicado no: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2015
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601060/ https://ncbi.nlm.nih.gov/pubmed/26487910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00287 |
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