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Lsh Is Essential for Maintaining Global DNA Methylation Levels in Amphibia and Fish and Interacts Directly with Dnmt1

Eukaryotic genomes are methylated at cytosine bases in the context of CpG dinucleotides, a pattern which is maintained through cell division by the DNA methyltransferase Dnmt1. Dramatic methylation losses are observed in plant and mouse cells lacking Lsh (lymphoid specific helicase), predominantly a...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Dunican, Donncha S., Pennings, Sari, Meehan, Richard R.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600896/
https://ncbi.nlm.nih.gov/pubmed/26491684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/740637
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