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The CXXC-TET bridge — mind the methylation gap!

CG-rich DNA “reader” proteins that bind non-methylated CpG sequences have emerged as critical factors to the process of cell differentiation and development. In a recent paper in Nature, Ko et al. show that the CXXC domain protein, IDAX, plays a crucial role as a CG-rich DNA-binding factor in the re...

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Detalhes bibliográficos
Main Authors: Dunican, Donncha S, Pennings, Sari, Meehan, Richard R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731560/
https://ncbi.nlm.nih.gov/pubmed/23711677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.71
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