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Genome-wide Analysis of Human Constitutive Androstane Receptor (CAR) Transcriptome in Wild-type and CAR-knockout HepaRG cells

The constitutive androstane receptor (CAR) modulates the transcription of numerous genes involving drug metabolism, energy homeostasis, and cell proliferation. Most functions of CAR however were defined from animal studies. Given the known species difference of CAR and the significant cross-talk bet...

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書誌詳細
出版年:Biochem Pharmacol
主要な著者: Li, Daochuan, Mackowiak, Bryan, Brayman, Timothy G., Mitchell, Michael, Zhang, Lei, Huang, Shiew-Mei, Wang, Hongbing
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600658/
https://ncbi.nlm.nih.gov/pubmed/26275810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.08.087
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