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Genome-wide Analysis of Human Constitutive Androstane Receptor (CAR) Transcriptome in Wild-type and CAR-knockout HepaRG cells

The constitutive androstane receptor (CAR) modulates the transcription of numerous genes involving drug metabolism, energy homeostasis, and cell proliferation. Most functions of CAR however were defined from animal studies. Given the known species difference of CAR and the significant cross-talk bet...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Li, Daochuan, Mackowiak, Bryan, Brayman, Timothy G., Mitchell, Michael, Zhang, Lei, Huang, Shiew-Mei, Wang, Hongbing
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600658/
https://ncbi.nlm.nih.gov/pubmed/26275810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.08.087
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