Multidrug Resistance Protein-4 Influences Aspirin Toxicity in Human Cell Line

Overexpression of efflux transporters, in human cells, is a mechanism of resistance to drug and also to chemotherapy. We found that multidrug resistance protein-4 (MRP4) overexpression has a role in reducing aspirin action in patients after bypass surgery and, very recently, we found that aspirin en...

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Veröffentlicht in:Mediators Inflamm
Hauptverfasser: Massimi, Isabella, Ciuffetta, Ambra, Temperilli, Flavia, Ferrandino, Francesca, Zicari, Alessandra, Pulcinelli, Fabio M., Felli, Maria Pia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600549/
https://ncbi.nlm.nih.gov/pubmed/26491233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/607957
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