Highly sensitive isotope-dilution liquid-chromatography–electrospray ionization–tandem-mass spectrometry approach to study the drug-mediated modulation of dopamine and serotonin levels in Caenorhabditis elegans

Dopamine (DA) and serotonin (SRT) are monoamine neurotransmitters that play a key role in regulating the central and peripheral nervous system. Their impaired metabolism has been implicated in several neurological disorders, such as Parkinson’s disease and depression. Consequently, it is imperative...

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Bibliographic Details
Published in:Talanta
Main Authors: Schumacher, Fabian, Chakraborty, Sudipta, Kleuser, Burkhard, Gulbins, Erich, Schwerdtle, Tanja, Aschner, Michael, Bornhorst, Julia
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600537/
https://ncbi.nlm.nih.gov/pubmed/26452793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.talanta.2015.05.057
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