Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry

Castration resistant prostate cancer (CRPC), the fatal form of prostate cancer, remains androgen dependent despite castrate levels of circulating testosterone (T) and 5α-dihydrotestosterone (DHT). To investigate mechanisms by which the tumor can synthesize its own androgens and develop resistance to...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Steroid Biochem Mol Biol
Main Authors: Zang, Tianzhu, Tamae, Daniel, Mesaros, Clementina, Wang, Qingqing, Huang, Meng, Blair, Ian A., Penning, Trevor M.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146996/
https://ncbi.nlm.nih.gov/pubmed/27531846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2016.08.001
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