Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry

Castration resistant prostate cancer (CRPC), the fatal form of prostate cancer, remains androgen dependent despite castrate levels of circulating testosterone (T) and 5α-dihydrotestosterone (DHT). To investigate mechanisms by which the tumor can synthesize its own androgens and develop resistance to...

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Vydáno v:J Steroid Biochem Mol Biol
Hlavní autoři: Zang, Tianzhu, Tamae, Daniel, Mesaros, Clementina, Wang, Qingqing, Huang, Meng, Blair, Ian A., Penning, Trevor M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146996/
https://ncbi.nlm.nih.gov/pubmed/27531846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2016.08.001
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