Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry

Castration resistant prostate cancer (CRPC), the fatal form of prostate cancer, remains androgen dependent despite castrate levels of circulating testosterone (T) and 5α-dihydrotestosterone (DHT). To investigate mechanisms by which the tumor can synthesize its own androgens and develop resistance to...

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Pubblicato in:J Steroid Biochem Mol Biol
Autori principali: Zang, Tianzhu, Tamae, Daniel, Mesaros, Clementina, Wang, Qingqing, Huang, Meng, Blair, Ian A., Penning, Trevor M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146996/
https://ncbi.nlm.nih.gov/pubmed/27531846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2016.08.001
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