Stable-Isotope Dilution HPLC-Electrospray Ionization Tandem Mass Spectrometry Method for Quantifying Hydroxyurea in Dried Blood Samples

BACKGROUND: Sickle cell anemia (SCA) is a life-threatening blood disorder characterized by the presence of sickle-shaped erythrocytes. Hydroxyurea is currently the only US Food and Drug Administration–approved treatment and there is a need for a convenient method to monitor compliance and hydroxyure...

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Bibliographic Details
Published in:Clin Chem
Main Authors: Marahatta, Anu, Megaraj, Vandana, McGann, Patrick T., Ware, Russell E., Setchell, Kenneth D.R.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598440/
https://ncbi.nlm.nih.gov/pubmed/27694393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2016.263715
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