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Loss of pdr-1/parkin influences Mn homeostasis through altered ferroportin expression in C. elegans
Overexposure to the essential metal manganese (Mn) can result in an irreversible condition known as manganism that shares similar pathophysiology with Parkinson’s disease (PD), including dopaminergic (DAergic) cell loss that leads to motor and cognitive impairments. However, the mechanisms behind th...
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| Опубликовано в: : | Metallomics |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4431931/ https://ncbi.nlm.nih.gov/pubmed/25769119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5mt00052a |
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