Loss of pdr-1/parkin influences Mn homeostasis through altered ferroportin expression in C. elegans

Overexposure to the essential metal manganese (Mn) can result in an irreversible condition known as manganism that shares similar pathophysiology with Parkinson’s disease (PD), including dopaminergic (DAergic) cell loss that leads to motor and cognitive impairments. However, the mechanisms behind th...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Metallomics
Asıl Yazarlar: Chakraborty, Sudipta, Chen, Pan, Bornhorst, Julia, Schwerdtle, Tanja, Schumacher, Fabian, Kleuser, Burkhard, Bowman, Aaron B., Aschner, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431931/
https://ncbi.nlm.nih.gov/pubmed/25769119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5mt00052a
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