A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells

A core set of autophagy proteins is required for gamma interferon (IFN-γ)-mediated clearance of Toxoplasma gondii in the mouse because of their control of several downstream effectors, including immunity-related GTPases (IRGs) and guanylate-binding proteins (GBPs). However, these effectors are absen...

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Pubblicato in:mBio
Autori principali: Selleck, Elizabeth M., Orchard, Robert C., Lassen, Kara G., Beatty, Wandy L., Xavier, Ramnik J., Levine, Beth, Virgin, Herbert W., Sibley, L. David
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Microbiology 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600106/
https://ncbi.nlm.nih.gov/pubmed/26350966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01157-15
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