High throughput screen identifies IFN-γ-dependent inhibitors of Toxoplasma gondii growth

Toxoplasma gondii is an obligate intracellular parasite capable of causing severe disease due to congenital infection and in patients with compromised immune systems. Control of infection is dependent on a robust Th1 type immune response including production of interferon gamma (IFN-γ), which is ess...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Infect Dis
Prif Awduron: Radke, Joshua B., Carey, Kimberly L., Shaw, Subrata, Metkar, Shailesh R., Mulrooney, Carol, Gale, Jennifer P., Bittker, Joshua A., Hilgraf, Robert, Comer, Eamon, Schreiber, Stuart L., Virgin, Herbert W., Perez, Jose R., Sibley, L. David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200635/
https://ncbi.nlm.nih.gov/pubmed/30058798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00135
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