High throughput screen identifies IFN-γ-dependent inhibitors of Toxoplasma gondii growth

Toxoplasma gondii is an obligate intracellular parasite capable of causing severe disease due to congenital infection and in patients with compromised immune systems. Control of infection is dependent on a robust Th1 type immune response including production of interferon gamma (IFN-γ), which is ess...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Radke, Joshua B., Carey, Kimberly L., Shaw, Subrata, Metkar, Shailesh R., Mulrooney, Carol, Gale, Jennifer P., Bittker, Joshua A., Hilgraf, Robert, Comer, Eamon, Schreiber, Stuart L., Virgin, Herbert W., Perez, Jose R., Sibley, L. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200635/
https://ncbi.nlm.nih.gov/pubmed/30058798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00135
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