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Artemisinin Induces Calcium-Dependent Protein Secretion in the Protozoan Parasite Toxoplasma gondii

Intracellular calcium controls several crucial cellular events in apicomplexan parasites, including protein secretion, motility, and invasion into and egress from host cells. The plant compound thapsigargin inhibits the sarcoplasmic-endoplasmic reticulum calcium ATPase (SERCA), resulting in elevated...

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Detalles Bibliográficos
Autores principales: Nagamune, Kisaburo, Beatty, Wandy L., Sibley, L. David
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168421/
https://ncbi.nlm.nih.gov/pubmed/17766463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00262-07
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