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Artemisinin Induces Calcium-Dependent Protein Secretion in the Protozoan Parasite Toxoplasma gondii

Intracellular calcium controls several crucial cellular events in apicomplexan parasites, including protein secretion, motility, and invasion into and egress from host cells. The plant compound thapsigargin inhibits the sarcoplasmic-endoplasmic reticulum calcium ATPase (SERCA), resulting in elevated...

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Detalhes bibliográficos
Main Authors: Nagamune, Kisaburo, Beatty, Wandy L., Sibley, L. David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168421/
https://ncbi.nlm.nih.gov/pubmed/17766463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00262-07
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