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Artemisinin Induces Calcium-Dependent Protein Secretion in the Protozoan Parasite Toxoplasma gondii

Intracellular calcium controls several crucial cellular events in apicomplexan parasites, including protein secretion, motility, and invasion into and egress from host cells. The plant compound thapsigargin inhibits the sarcoplasmic-endoplasmic reticulum calcium ATPase (SERCA), resulting in elevated...

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Bibliographische Detailangaben
Hauptverfasser: Nagamune, Kisaburo, Beatty, Wandy L., Sibley, L. David
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168421/
https://ncbi.nlm.nih.gov/pubmed/17766463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00262-07
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