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Artemisinin-Resistant Mutants of Toxoplasma gondii Have Altered Calcium Homeostasis

Artemisinin is a plant sesquiterpene lactone that has become an important drug for combating malaria, especially in regions where resistance to other drugs is widespread. While the mechanism of action is debated, artemisinin has been reported to inhibit the sarcoplasmic endoplasmic reticulum Ca(2+)...

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Hlavní autoři: Nagamune, Kisaburo, Moreno, Silvia N. J., Sibley, L. David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151471/
https://ncbi.nlm.nih.gov/pubmed/17698618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00582-07
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