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Perforin-2/Mpeg1 and other pore-forming proteins throughout evolution

Development of the ancient innate immune system required not only a mechanism to recognize foreign organisms from self but also to destroy them. Pore-forming proteins containing the membrane attack complex Perforin domain were one of the first triumphs of an innate immune system needing to eliminate...

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Détails bibliographiques
Publié dans:J Leukoc Biol
Auteurs principaux: McCormack, Ryan, Podack, Eckhard R.
Format: Artigo
Langue:Inglês
Publié: Society for Leukocyte Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600061/
https://ncbi.nlm.nih.gov/pubmed/26307549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4MR1114-523RR
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