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Inhibition of Intracellular Bacterial Replication in Fibroblasts Is Dependent on the Perforin-Like Protein (Perforin-2) Encoded by Macrophage-Expressed Gene 1
Fibroblasts are known to eliminate intracellular bacteria, but the lethal hit of the bactericidal mechanism has not been defined. We show that primary embryonic and established fibroblasts can be induced by interferons or by intracellular bacterial infection to express a perforin-like mRNA previousl...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732477/ https://ncbi.nlm.nih.gov/pubmed/23257510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000345249 |
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