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Killing machines: three pore-forming proteins of the immune system
The evolution of early multicellular eukaryotes 400–500 million years ago required a defensive strategy against microbial invasion. Pore-forming proteins containing the membrane-attack-complex-perforin (MACPF) domain were selected as the most efficient means to destroy bacteria or virally infected c...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3980504/ https://ncbi.nlm.nih.gov/pubmed/24293008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-013-8469-9 |
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