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Killing machines: three pore-forming proteins of the immune system

The evolution of early multicellular eukaryotes 400–500 million years ago required a defensive strategy against microbial invasion. Pore-forming proteins containing the membrane-attack-complex-perforin (MACPF) domain were selected as the most efficient means to destroy bacteria or virally infected c...

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書目詳細資料
Main Authors: McCormack, Ryan, de Armas, Lesley, Shiratsuchi, Motoaki, Podack, Eckhard R.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980504/
https://ncbi.nlm.nih.gov/pubmed/24293008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-013-8469-9
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